Searchable abstracts of presentations at key conferences in endocrinology

ea0021p141 | Diabetes and metabolism | SFEBES2009

Diabetic keto-acidosis in patients with Type 2 diabetes mellitus: a relatively common occurrence, the severity of which correlates with HbA1c

Begbie Helen , Barber Thomas , Reddy Narendra , Simpson Hugh

Aims: Our aim was to explore factors related to the acute presentation of diabetic keto-acidosis (DKA) in patients with Type 2 diabetes mellitus (T2D), and to identify any predictors for severity of DKA in T2D.Methods: This was a retrospective study based on acute medical admissions presenting to the Royal Berkshire Hospital during 2008. Criteria for inclusion included a confirmed diagnosis of DKA (defined by a plasma glucose level >11.1 mmol/l, keto...

ea0021p163 | Diabetes and metabolism | SFEBES2009

An exploration of the predictive factors for the early pleiotropic responses to exenatide therapy in patients with type 2 diabetes mellitus

Barber Thomas , Reddy Narendra , Begbie Helen , Sophal Naseem , McCulloch Carol , Rogers Angela , Naziat Auditi , Ghosh Diptendra , Mukhtar Mamoun , Simpson Hugh

Aims: Our aim was to explore predictive factors for the pleiotropic responses to exenatide during the first 12 weeks of therapy, and associations between these responses.Methods: This was an observational study based on patients (n=83) with type 2 diabetes mellitus (T2D) in whom exenatide had been added to existing oral hypoglycaemic therapy. Exenatide was administered subcutaneously (5 mcg bd for the first month, 10 mcg bd thereafter). Data colle...